Pazopanib is an anticancer medicine that is used to treat adults with kidney cancer (advanced renal cell carcinoma). It is also used to treat advanced soft tissue sarcoma (STS) in patients who have received cancer treatments.
Pazopanib interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by pazopanib, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.
This drug is a type of targeted therapy known as a known as a kinase inhibitor. Kinases are proteins on or near the surface of a cell that transmit signals to the cell’s control center. Pazopanib inhibits several kinase proteins (VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-A, PDGFR-B, FGFR-1, FGFR-3, Kit, Itk, Lck, and c-Fms). These proteins either prompt tumor cells to grow and divide or help form new blood vessels (angiogenesis) that feed the tumor. By blocking these proteins, pazopanib may help stop the growth of cancer cells.
from:Acridine Raw Material
Pazopanib interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by pazopanib, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.
This drug is a type of targeted therapy known as a known as a kinase inhibitor. Kinases are proteins on or near the surface of a cell that transmit signals to the cell’s control center. Pazopanib inhibits several kinase proteins (VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-A, PDGFR-B, FGFR-1, FGFR-3, Kit, Itk, Lck, and c-Fms). These proteins either prompt tumor cells to grow and divide or help form new blood vessels (angiogenesis) that feed the tumor. By blocking these proteins, pazopanib may help stop the growth of cancer cells.
from:Acridine Raw Material
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