Salvianolic acid B (SAB, Sal B) is the adumbrative basic of phenolic acids acquired from the broiled base and base of Salvia miltiorrhiza Bge (Labiatae) which has been acclimated broadly and auspiciously in Asian countries for analytic analysis of assorted vascular disturbance-related diseases for hundreds of years. However, its exact cardioprotective apparatus and the basal apparatus for ameliorative base are still ailing understood.
Salvianolic acid B is a corpuscle careful antioxidant and chargeless abolitionist scavenger getting advised for a array of altitude from ischemic affection disorders to Alzheimer′s disease. Several mechanisms of action accept been proposed including EGFR, PDGF and MMP-9 inhibition and inhibition of the TGF-β1/Smads and NF-κB signaling pathways. Salvianolic acid B acts as scavengers of acknowledging oxygen species, reduces the adherence of leukocytes to endothelial cells, inhibits cast metalloproteinases and inflammation. It has cardioprotective furnishings as it reduces lipid peroxidation in damaged cardiac tissue and decreases the arising of lactic acid dehydrogenase.
from:Natural standard substance
Salvianolic acid B is a corpuscle careful antioxidant and chargeless abolitionist scavenger getting advised for a array of altitude from ischemic affection disorders to Alzheimer′s disease. Several mechanisms of action accept been proposed including EGFR, PDGF and MMP-9 inhibition and inhibition of the TGF-β1/Smads and NF-κB signaling pathways. Salvianolic acid B acts as scavengers of acknowledging oxygen species, reduces the adherence of leukocytes to endothelial cells, inhibits cast metalloproteinases and inflammation. It has cardioprotective furnishings as it reduces lipid peroxidation in damaged cardiac tissue and decreases the arising of lactic acid dehydrogenase.
from:Natural standard substance
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