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Gonadotrophin is to adjust development in vertebrates, promoting sexual hormones and glycoprotein hormone secretion. Such as the production of pituitary secretion of luteinizing hormone (LH) and mature follicle stimulating hormone (FSH), both synergy, stimulate the ovaries or testicular germ cell development and in the generation and secretion of sex hormones; Person placenta secretes human chorionic gonadotropin (HCG), can promote pregnancy corpus luteum secretion of progesterone. Early pregnancy urine HCG, appeared in the two months of pregnancy when peak, clinical indicators often as pregnancy.

Function: LH is also called promoting stromal cell hormone (ICSH), because of its role in testis interstitial cells, stimulate the generation and secretion of testosterone. LH ovaries of female animals as the main function of selective before ovulation induction of individual follicles grew rapidly, and LH secretion reach orgasm, trigger ovulation and after ovulation follicle walls into corpus luteum and secretion of progesterone. FSH is to promote the importance of ovarian follicle growth and development, in the male promote testicular sperm formation in seminiferous tubule.

Application: preparing from animal pituitary gonadotropins, has been widely used in animal husbandry, aquaculture, but invalid to mankind. From the women urine HCG can be produced, or extracted from menopausal women urine a mixture of LH and FSH preparations, referred to as "human menopausal gonadotropin (HMG), can be used for treatment of hypogonadism disease clinically.

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